Darlene Cates Loses 250 Lbs., Sets Sights on Acting Again

Darlene Cates was unforgettable in What’s Eating Gilbert Grape, playing Johnny Depp and Leonardo DiCaprio’s morbidly obese mother Bonnie, who hasn’t left the house in years while in the grips of depression following her husband’s suicide.

Now, almost 20 years and a number of health problems later, Cates, 64, has lost nearly 250 lbs. – and is feeling optimistic that she might act again.