updated 12/11/2008 AT 8:00 AM ET
•originally published 12/11/2008 AT 8:20 AM ET
He will likely be replaced by Ben Stiller in the film, written and directed by Noah Baumbach, says the trade paper.
No reason was given for the casting shakeup. But the news comes just three days after Scott Ruffalo succumbed to a gunshot wound he sustained Dec. 1.
In a statement after the death, Mark Ruffalo said that he and his family “deeply appreciate the outpouring of prayers and support during this most difficult time.”